PRMT4/CARM1 Mouse mAb
Source: Mouse mAb Catalog No. : AB3112
PRMT4/CARM1 Mouse mAb (AB3112)
UniProt:Q86X55
Application:WB,IP
Reactivity:Human,Mouse
Source:Mouse mAbhttp://www.abways.cn/showproduct.asp?cid=AB3112
数据表
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UniProt
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Mol Weight63KDa
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Alternative NamesHistone arginine methyltransferase CARM 1; Histone arginine methyltransferase CARM1; PRMT4; Protein arginine N methyltransferase 4;
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ImmunogenPurified recombinant human PRMT4/CARM1 protein fragments expressed in E.coli.
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StorageMouse IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeMouse IgG1
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ClonalityMonoclonal
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DescriptionMethylates (mono- and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in several proteins involved in DNA packaging, transcription regulation, pre-mRNA splicing, and mRNA stability. Recruited to promoters upon gene activation together with histone acetyltransferases from EP300/P300 and p160 families, methylates histone H3 at 'Arg-17' (H3R17me), forming mainly asymmetric dimethylarginine (H3R17me2a), leading to activate transcription via chromatin remodeling.
Applications
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ReactivityHuman,Mouse
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ApplicationWB,IP
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Recommended dilutionWB 1:200-500 IP
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Western blot detection of PRMT4/CARM1 in Hela,A431 and K562 cell lysates using PRMT4/CARM1 mouse mAb (1:200-1:500 diluted).Predicted band size:63KDa.Observed band size:63KDa. -
Immunoprecipitation analysis of Hela cell lysates using PRMT4/CARM1 mouse mAb.
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