SIRT6 Mouse mAb
Source: Mouse mAb Catalog No. : AB3170
SIRT6 Mouse mAb (AB3170)
UniProt:Q8N6T7
Application:WB,ICC/IF,IP
Reactivity:Human,Mouse,Rat,Monkey
Source:Mouse mAbhttp://www.abways.cn/showproduct.asp?cid=AB3170
数据表
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UniProt
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Mol Weight42KDa
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Alternative NamesSIR2L6; SIR2-like protein 6; NAD-dependent protein deacetylase sirtuin-6; Regulatory protein SIR2 homolog 6; Sirtuin 6;
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ImmunogenPurified recombinant human SIRT6 protein expressed in E.coli.
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StorageMouse IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeMouse IgG1
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ClonalityMonoclonal
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DescriptionNAD-dependent protein deacetylase. Has deacetylase activity towards histone H3K9Ac and H3K56Ac. Modulates acetylation of histone H3 in telomeric chromatin during the S-phase of the cell cycle. Deacetylates histone H3K9Ac at NF-kappa-B target promoters and
Applications
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ReactivityHuman,Mouse,Rat,Monkey
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ApplicationWB,ICC/IF,IP
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Recommended dilutionWB 1:500 ICC/IF 1:100 IP
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Western blot analysis of extracts from Jurkat,MCF7,HCT116,K562,COS7,C2C12,3T3 and Hela cell lysates using SIRT6 mouse mAb (1:500 diluted).Predicted band size:42,36KDa.Observed band size:42,36KDa. -
Immunofluorescent analysis of Hela cells fixed fixed by 4% paraformaldehyde and using SIRT6 mouse mAb (dilution 1:100). -
Immunoprecipitation analysis of Hela cell lysates using SIRT6 mouse mAb.
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