Cyclin D2 Mouse mAb
Source: Mouse mAb Catalog No. : AB3171
Cyclin D2 Mouse mAb (AB3171)
UniProt:P30279
Application:WB
Reactivity:Human
Source:Mouse mAbhttp://www.abways.cn/showproduct.asp?cid=AB3171
数据表
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UniProt
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Mol Weight38KDa
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Alternative NamesCCND 2; CCND2; CyclinD2; G1/S specific cyclin D2; G1/S-specific cyclin-D2;
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ImmunogenPurified recombinant human Cyclin D2 protein fragments expressed in E.coli.
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StorageMouse IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeMouse IgG2b
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ClonalityMonoclonal
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DescriptionRegulatory component of the cyclin D2-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G1/S transition.Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G1 phase.
Applications
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ReactivityHuman
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ApplicationWB
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Recommended dilutionWB 1:1000
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Western blot detection of Cyclin D2 in CHO-K1 cell lysate（A）and CHO-K1 transfected by Cyclin D2-fragment EGFP fusion protein（B）cell lysate using Cyclin D2 mouse mAb (1:1000 diluted).Predicted band size:38KDa.Observed band size:38KDa.
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