BTK Mouse mAb
Source: Mouse mAb Catalog No. : AB3189
BTK Mouse mAb (AB3189)
UniProt:Q06187
Application:WB,IP
Reactivity:Human
Source:Mouse mAbhttp://www.abways.cn/showproduct.asp?cid=AB3189
数据表
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UniProt
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Mol Weight77KDa
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Alternative NamesAgammaglobulinaemia tyrosine kinase; AGMX1; ATK; B cell progenitor kinase; BPK; Bruton's tyrosine kinase; EC 2.7.10.2; kinase Btk; Kinase EMB;
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ImmunogenPurified recombinant human BTK protein fragments expressed in E.coli.
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StorageMouse IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeMouse IgG1
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ClonalityMonoclonal
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DescriptionNon-receptor tyrosine kinase indispensable for B lymphocyte development, differentiation and signaling. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. After BCR engagement and activation at the plasma membrane, phosphorylates PLCG2 at several sites, igniting the downstream signaling pathway through calcium mobilization, followed by activation of the protein kinase C (PKC) family members.
Applications
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ReactivityHuman
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ApplicationWB,IP
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Recommended dilutionWB 1:1000 IP
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Western blot detection of BTK in Daudi,Jurkat(BTK negative),K562,Ramos and Raji cell lysates using BTK mouse mAb (1:1000 diluted).Predicted band size:77KDa.Observed band size:77KDa. -
Immunoprecipitation analysis of Raji cell lysates using BTK mouse mAb.
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