FYB Mouse mAb
Source: Mouse mAb Catalog No. : AB3214
FYB Mouse mAb (AB3214)
UniProt:O15117
Application:WB
Reactivity:Human
Source:Mouse mAbhttp://www.abways.cn/showproduct.asp?cid=AB3214
数据表
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UniProt
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Mol Weight120KDa
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Alternative NamesFYB; ADAP; FYN-binding protein; FYN-T-binding protein; FYB-120/130; FYN binding protein; p120/p130; PRO0823; SLAP130;
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ImmunogenPurified recombinant human FYB protein fragments expressed in E.coli.
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StorageMouse IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeMouse IgG1
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ClonalityMonoclonal
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DescriptionActs as an adapter protein of the FYN and LCP2 signaling cascades in T-cells.Modulates the expression of interleukin-2 (IL-2).Involved in platelet activation.Prevents the degradation of SKAP1 and SKAP2.May play a role in linking T-cell signaling to remodeling of the actin cytoskeleton.
Applications
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ReactivityHuman
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ApplicationWB
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Recommended dilutionWB 1:500
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Western blot detection of FYB in 10,20 and 30ug Jurkat cell lysate using FYB mouse mAb (1:500 diluted).Predicted band size:120KDa.Observed band size:120KDa.
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