CrkII Mouse mAb_单克隆抗体-上海泊湾生物技术有限公司

CrkII Mouse mAb

Source: Mouse mAb Catalog No. : AB3234

CrkII Mouse mAb (AB3234)
UniProt:P46108
Application:WB
Reactivity:Human
Source:Mouse mAbhttp://www.abways.cn/showproduct.asp?cid=AB3234

数据表

UniProt

P46108
Mol Weight

34KDa
Alternative Names

Adapter molecule crk; CRK; CRKII;
Immunogen

Purified recombinant human CrkII protein fragments expressed in E.coli.
Storage

Mouse IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Purification

Affinity-chromatography
Isotype

Mouse IgG2b
Clonality

Monoclonal
Description

The Crk-I and Crk-II forms differ in their biological activities. Crk-II has less transforming activity than Crk-I. Crk-II mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4.

Applications

Western blot detection of CrkII in Lncap,A431,MCF7 and HT1080 cell lysates using CrkII mouse mAb (1:1000 diluted).Predicted band size: 34kDa.Observed band size: 34kDa.