DDB1 Mouse mAb
Source: Mouse mAb Catalog No. : AB3260
DDB1 Mouse mAb (AB3260)
UniProt:Q16531
Application:WB
Reactivity:Human,Mouse,Rat,Monkey
Source:Mouse mAbhttp://www.abways.cn/showproduct.asp?cid=AB3260
数据表
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UniProt
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Mol Weight127KDa
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Alternative NamesXPE; DDBA; XAP1; XPCE; XPE-BF; UV-DDB1;
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ImmunogenPurified recombinant human DDB1 protein fragments expressed in E.coli.
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StorageMouse IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeMouse IgG2b
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ClonalityMonoclonal
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DescriptionRequired for DNA repair.Binds to DDB2 to form the UV-damaged DNA-binding protein complex (the UV-DDB complex).The UV-DDB complex may recognize UV-induced DNA damage and recruit proteins of the nucleotide excision repair pathway (the NER pathway) to initiate DNA repair.The UV-DDB complex preferentially binds to cyclobutane pyrimidine dimers (CPD),6-4 photoproducts (6-4 PP),apurinic sites and short mismatches.
Applications
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ReactivityHuman,Mouse,Rat,Monkey
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ApplicationWB
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Recommended dilutionWB 1:1000
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Western blot detection of DDB1 in Hela,MCF7,COS7,C6 and 3T3 cell lysates using DDB1 mouse mAb (1:1000 diluted),with Super ECL.Predicted band size:127KDa.Observed band size:127KDa.
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