FAK Mouse mAb
Source: Mouse mAb Catalog No. : AB3262
FAK Mouse mAb (AB3262)
UniProt:Q05397
Application:WB,ICC/IF
Reactivity:Human
Source:Mouse mAbhttp://www.abways.cn/showproduct.asp?cid=AB3262
数据表
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UniProt
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Mol Weight125KDa
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Alternative NamesFAK; FADK; FAK1; FRNK; pp125FAK; PTK2;
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ImmunogenPurified recombinant human FAK protein fragments expressed in E.coli.
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StorageMouse IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeMouse IgG1
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ClonalityMonoclonal
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DescriptionNon-receptor protein-tyrosine kinase that plays an essential role in regulating cell migration, adhesion, spreading, reorganization of the actin cytoskeleton, formation and disassembly of focal adhesions and cell protrusions, cell cycle progression, cell proliferation and apoptosis. Required for early embryonic development and placenta development. Required for embryonic angiogenesis, normal cardiomyocyte migration and proliferation, and normal heart development.
Applications
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ReactivityHuman
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ApplicationWB,ICC/IF
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Recommended dilutionWB 1:1000 ICC/IF 1:200
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Western blot detection of FAK in COS7,HUVEC,A549 and Hela cell lysates using FAK mouse mAb (1:1000 diluted).Predicted band size: 125KDa.Observed band size:125KDa. -
Immunofluorescent analysis of Hela cells fixed fixed by anhydrous methanol at -20℃ and using FAK mouse mAb (dilution 1:200).
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