Prominin-1 Mouse mAb
Source: Mouse mAb Catalog No. : AB3271
Prominin-1 Mouse mAb (AB3271)
UniProt:O43490
Application:WB
Reactivity:Human
Source:Mouse mAbhttp://www.abways.cn/showproduct.asp?cid=AB3271
数据表
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UniProt
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Mol Weight133KDa
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Alternative NamesProminin-1; Prominin-like protein 1; RP41; AC133; CD133; MCDR2; STGD4; CORD12; PROML1;
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ImmunogenPurified recombinant human Prominin-1 protein fragments expressed in E.coli.
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StorageMouse IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeMouse IgG2b
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ClonalityMonoclonal
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DescriptionBinds cholesterol in cholesterol-containing plasma membrane microdomains.Proposed to play a role in apical plasma membrane organization of epithelial cells.During early retinal development acts as a key regulator of disk morphogenesis.Involved in regulation of MAPK and Akt signaling pathways.In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner.
Applications
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ReactivityHuman
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ApplicationWB
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Recommended dilutionWB 1:3000
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Western blot detection of Prominin-1 in CaCo2 cell lysate using Prominin-1 mouse mAb (1:3000 diluted).Predicted band size:133KDa.Observed band size:133KDa
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