Bax Mouse mAb
Source: Mouse mAb Catalog No. : AB3280
Bax Mouse mAb (AB3280)
UniProt:Q07812
Application:WB
Reactivity:Human,Monkey
Source:Mouse mAb
References（1）
http://www.abways.cn/showproduct.asp?cid=AB3280
数据表
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UniProt
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Mol Weight20KDa
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Alternative NamesApoptosis regulator BAX; BAX; Bcl-2-like protein 4; BCL2-associated X protein; Bcl2-L-4; BCL2L4
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ImmunogenPurified recombinant human Bax protein fragments expressed in E.coli
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StorageMouse IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeMouse IgG2a
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ClonalityMonoclonal
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DescriptionAccelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis.
Applications
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ReactivityHuman,Monkey
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ApplicationWB
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Recommended dilutionWB 1:1000
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Western blot detection of Bax in COS7,Raji,CEM and Hela cell lysates using Bax mouse mAb (1:1000 diluted). Predicted band size:20KDa. Observed band size:20KDa.
引用文献（1条）
Self-Assembled/Drug-Composed Nanomedicine for Synergistic Photonic Hyperthermia and Targeted Therapy of Breast Cancer by Inhibiting ERK, AKT, and STAT3 Signaling Cascades-VETERINARY RESEARCH(VET RES)
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