BRAP Mouse mAb
Source: Mouse mAb  Catalog No. : AB3286  
BRAP Mouse mAb (AB3286)
UniProt:Q7Z569
Application:WB
Reactivity:Human
Source:Mouse mAbhttp://www.abways.cn/showproduct.asp?cid=AB3286
数据表
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UniProt
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Mol Weight67KDa
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Alternative NamesBRAP; BRAP2; IMP; Galectin-2-binding protein; RING finger protein 52; RNF52; BRCA1 associated protein;
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ImmunogenPurified recombinant human BRAP protein fragments expressed in E.coli.
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StorageMouse IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeMouse IgG1
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ClonalityMonoclonal
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DescriptionNegatively regulates MAP kinase activation by limiting the formation of Raf/MEK complexes probably by inactivation of the KSR1 scaffold protein. Also acts as a Ras responsive E3 ubiquitin ligase that, on activation of Ras, is modified by auto-polyubiquitination resulting in the release of inhibition of Raf/MEK complex formation.
Applications
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ReactivityHuman
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ApplicationWB
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Recommended dilutionWB 1:500-1000

 
 
 

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