Caspase-9 Mouse mAb
Source: Mouse mAb Catalog No. : AB3290
Caspase-9 Mouse mAb (AB3290)
UniProt:P55211
Application:WB
Reactivity:Human,Transfected
Source:Mouse mAb
References（1）
http://www.abways.cn/showproduct.asp?cid=AB3290
数据表
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UniProt
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Mol Weight49,37KDa
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Alternative NamesAPAF-3; ICE-LAP6; Apoptotic protease Mch-6; Apoptotic protease activating factor 3; CASP-9; Caspase-9 precursor; ICE-like apoptotic protease 6; MCH6; RNCASP9
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ImmunogenPurified recombinant human Caspase-9 protein fragments expressed in E.coli.
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StorageMouse IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeMouse IgG1
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ClonalityMonoclonal
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DescriptionInvolved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner.
Applications
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ReactivityHuman,Transfected
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ApplicationWB
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Recommended dilutionWB 1:1000
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Western blot detection of Caspase-9 in A549,MCF7,Jurkat,K562 and Hela cell lysates using Caspase-9 mouse mAb (1:1000 diluted).Predicted band size:49/37KDa.Observed band size:49KDa.
引用文献（1条）
CXCL3 overexpression affects the malignant behavior of oral squamous cell carcinoma cells via the MAPK signaling pathway-JOURNAL OF ORAL PATHOLOGY & MEDICINE (J ORAL PATHOL MED)
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