EGF Receptor Mouse mAb
Source: Mouse mAb Catalog No. : AB3301
EGF Receptor Mouse mAb (AB3301)
UniProt:P00533
Application:WB,ICC/IF,IP
Reactivity:Human,Monkey
Source:Mouse mAbhttp://www.abways.cn/showproduct.asp?cid=AB3301
数据表
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UniProt
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Mol Weight175KDa
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Alternative NamesEC 2.7.10.1; Receptor protein-tyrosine kinase ErbB-1; kinase EGFR; ERBB1; Epidermal growth factor receptor precursor
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ImmunogenPurified recombinant human EGFR protein fragments expressed in E.coli.
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StorageMouse IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeMouse IgG1
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ClonalityMonoclonal
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DescriptionReceptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues.
Applications
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ReactivityHuman,Monkey
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ApplicationWB,ICC/IF,IP
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Recommended dilutionWB 1:2000 ICC/IF 1:200 IP
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Western blot detection of EGFR in A549 and COS7 cell lysates using EGFR mouse mAb(dilution 1:2000).Predicted band size:134 Kda.Observed band size:175KDa. -
Immunofluorescent analysis of HeLa cells using EGFR mouse mAb (dilution 1:200). -
Immunoprecipitation analysis of Hela cell lysates using EGFR mouse mAb.
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