SIRT1 Mouse mAb
Source: Mouse mAb Catalog No. : AB3309
SIRT1 Mouse mAb (AB3309)
UniProt:Q96EB6
Application:WB,IP
Reactivity:Human
Source:Mouse mAbhttp://www.abways.cn/showproduct.asp?cid=AB3309
数据表
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UniProt
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Mol Weight120KDa
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Alternative NameshSIR2; hSIRT1; NAD-dependent deacetylase sirtuin 1; SIR1; SIR2-like protein 1; SIR2L1; sirtuin 1
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ImmunogenPurified recombinant human SIRT1 protein fragments expressed in E.coli.
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StorageMouse IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeMouse IgG2b
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ClonalityMonoclonal
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DescriptionNAD+/NADH which is altered by glucose deprivation and metabolic changes associated with caloric restriction.Is essential in skeletal muscle cell differentiation and in response to low nutrients mediates the inhibitory effect on skeletal myoblast differentiation which also involves 5'-AMP-activated protein kinase (AMPK) and nicotinamide phosphoribosyltransferase (NAMPT).
Applications
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ReactivityHuman
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ApplicationWB,IP
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Recommended dilutionWB 1:1000 IP
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Western blot detection of SIRT1 in Hela,Jurkat,Ramos,A549 and CEM cell lysates using SIRT1 mouse mAb (1:1000 diluted).Predicted band size:120KDa.Observed band size:120KDa. -
Immunoprecipitation analysis of Hela cell lysates using SIRT1 mouse mAb.
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