β-Arrestin 1 Mouse mAb
Source: Mouse mAb Catalog No. : AB3380
β-Arrestin 1 Mouse mAb (AB3380)
UniProt:P49407
Application:WB
Reactivity:Human
Source:Mouse mAbhttp://www.abways.cn/showproduct.asp?cid=AB3380
数据表
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UniProt
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Mol Weight51KDa
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Alternative NamesARB1; ARR1; ARRB1; Arrestin 2; Arrestin beta 1; Arrestin beta-1; Beta-arrestin-1.
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ImmunogenRecombinant human β-Arrestin 1 protein.
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StorageMouse IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeMouse IgG2b
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ClonalityMonoclonal
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DescriptionFunctions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta-arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation.
Applications
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ReactivityHuman
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ApplicationWB
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Recommended dilutionWB 1:500
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Western blot detection of β-Arrestin 1 in K562 and Hela cell lysates using β-Arrestin 1 mouse mAb(dilution 1:500).Predicted band size:51kDa.Observed band size:51kDa.
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