Eph receptor B1 (9B4) Mouse mAb
Source: Mouse mAb Catalog No. : AB3430
Eph receptor B1 (9B4) Mouse mAb (AB3430)
UniProt:P54762
Application:WB,IHC
Reactivity:Human
Source:Mouse mAbhttp://www.abways.cn/showproduct.asp?cid=AB3430
数据表
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UniProt
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Mol Weight110kDa
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Alternative NamesELK; NET; Hek6; EPHT2; EPHB1
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ImmunogenPurified recombinant fragment of EphB1 (aa19-133) expressed in E. Coli.
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StorageMouse IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeMouse IgG1
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ClonalityMonoclonal
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DescriptionSwiss-Prot Acc.P54762.EhpB1: EPH receptor B1. It is a receptor for ephrin-B family members. Ephrin receptors and their ligands, the ephrins, medate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family.
Applications
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ReactivityHuman
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ApplicationWB,IHC
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Recommended dilutionWB: 1/500-1/1000 IHC: 1/50-1/100
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Western blot analysis using EhpB1 mouse mAb against MDA-MB-468 (1), MDA-MB-453 (2), MCF-7 (3), T47D (4) and SKBR-3 (5) cell lysate. -
Immunohistochemical analysis of paraffin-embedded human lung cancer (left) and colon cancer (right) showing cytoplasmic localization with DAB staining using EphB1 mouse mAb.
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