PAK2 (7H3) Mouse mAb
Source: Mouse mAb Catalog No. : AB3435
PAK2 (7H3) Mouse mAb (AB3435)
UniProt:Q13177
Application:WB,IHC,ICC/IF
Reactivity:Human,Monkey
Source:Mouse mAbhttp://www.abways.cn/showproduct.asp?cid=AB3435
数据表
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UniProt
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Mol Weight61kDa
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Alternative NamesPAK65; PAKgamma
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ImmunogenPurified recombinant fragment of PAK2 expressed in E. Coli.
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StorageMouse IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeMouse IgG1
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ClonalityMonoclonal
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DescriptionSwiss-Prot Acc.Q13177.PAK2, also known as P21 (CDKN1A)-activated kinase 2. The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. PAK2 is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. PAK2 has been shown to interact with SH3KBP1, CDC42 and Abl gene.
Applications
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ReactivityHuman,Monkey
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ApplicationWB,IHC,ICC/IF
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Recommended dilutionWB: 1/500-1/1000 IHC: 1/50-1/100 ICC/IF: 1/50-1/200
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Western blot detection of PAK2 in Jurkat,MCF7 and Hela cell lysates using PAK2 mouse mAb (1:5000 diluted).Predicted band size:61KDa.Observed band size:61KDa. -
Immunohistochemical analysis of paraffin-embedded human lung cancer (left) and gastric cancer (right) using PAK2 mouse mAb with DAB staining. -
Confocal immunofluorescence analysis of Hela cells using PAK2 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye.
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