Synaptophysin (10C8) Mouse mAb
Source: Mouse mAb Catalog No. : AB3437
Synaptophysin (10C8) Mouse mAb (AB3437)
UniProt:P08247
Application:WB,IHC
Reactivity:Human,Mouse,Rat
Source:Mouse mAbhttp://www.abways.cn/showproduct.asp?cid=AB3437
数据表
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UniProt
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Mol Weight33.8kDa
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Alternative NamesMRXSYP; SYP
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ImmunogenPurified recombinant fragment of SYP expressed in E. Coli.
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StorageMouse IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeMouse IgG1
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ClonalityMonoclonal
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DescriptionSwiss-Prot Acc.P08247.Synaptophysin (p38) is an integral membrane protein of small synaptic vesicles in brain and endocrine cells.Synaptophysin contains four transmembrane domains that form a hexameric channel or gap junction-like pore. Synaptophysin binds to the SNARE protein synaptobrevin/VAMP, which prevents the inclusion of synaptobrevin in the synaptic vesicle fusion complex and creates a pool of synaptobrevin for exocytosis when synapse activity increases. Synaptophysin is also responsible for targeting synaptobrevin 2/VAMP2 to synaptic vesicles, a critical component of the fusion complex.
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB,IHC
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Recommended dilutionWB: 1/500-1/1000 IHC: 1/50-1/100
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Western blot detection of Synaptophysin in Rat Brain,Rat Hippocampus,Hela,3T3 cell lysates using Synaptophysin (1C8) Mouse mAb(1:1000 diluted).Predicted band size:33.8KDa.Observed band size:38KDa. -
Immunohistochemical analysis of paraffin-embedded human Small Intestine, myenteric plexus tissues using anti-SYP mouse mAb.
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