MCM2 (2B5) Mouse mAb
Source: Mouse mAb Catalog No. : AB3440
MCM2 (2B5) Mouse mAb (AB3440)
UniProt:P49736
Application:WB,IHC,ICC/IF,FC,IP
Reactivity:Human
Source:Mouse mAbhttp://www.abways.cn/showproduct.asp?cid=AB3440
数据表
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UniProt
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Mol Weight125kDa
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Alternative NamesBM28; CCNL1; CDCL1; cdc19; D3S3194; MITOTIN; KIAA0030; MGC10606
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ImmunogenPurified recombinant fragment of human MCM2 expressed in E. Coli.
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StorageMouse IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeMouse IgG1
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ClonalityMonoclonal
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DescriptionSwiss-Prot Acc.P49736.The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7.
Applications
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ReactivityHuman
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ApplicationWB,IHC,ICC/IF,FC,IP
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Recommended dilutionWB: 1/500-1/1000 IHC: 1/50-1/100 ICC/IF: 1/50-1/200 IP: 1/20 FC: 1/50-1/100
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Western blot detection of MCM2 in Jurkat,K562,3T3 and Hela cell lysates using MCM2 mouse mAb (1:3000 diluted).Predicted band size:125KDa.Observed band size:125KDa. -
Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues using MCM2 mouse mAb with DAB staining. -
Immunofluorescence analysis of Hela cells using MCM2 mouse mAb (green). Blue -
Immunoprecipitation analysis of Hela cell lysates using MCM2 mouse mAb.
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