Peroxiredoxin 1/PAG (6A6) Mouse mAb_单克隆抗体-上海泊湾生物技术有限公司

Peroxiredoxin 1/PAG (6A6) Mouse mAb

Source: Mouse mAb Catalog No. : AB3459

Peroxiredoxin 1/PAG (6A6) Mouse mAb (AB3459)
UniProt:Q06830
Application:WB,IHC,ICC/IF
Reactivity:Human,Mouse,Rat
Source:Mouse mAbhttp://www.abways.cn/showproduct.asp?cid=AB3459

 Datasheet

数据表

UniProt

Q06830
Mol Weight

21kDa
Alternative Names

Hbp23, Heme binding 23kDa protein, Macrophage stress protein 22kDa, MSP23, NKEF A, Prdx1
Immunogen

Recombinant Protein of Peroxiredoxin-1
Storage

Mouse IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Purification

Affinity-chromatography
Isotype

Mouse IgG1
Clonality

Monoclonal
Description

Swiss-Prot Acc.Q06830.Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H2O2 (PubMed:9497357). Reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation .

Applications

Reactivity

Human,Mouse,Rat
Application

WB,IHC,ICC/IF
Recommended dilution

WB: 1/500-1/3000 IHC: 1/50-1/100 ICC/IF: 1/50-1/200

Western blot detection of Prdx 1 in T47D,3T3,COS7,C6 and Hela cell lysates using Prdx 1 mouse mAb (1:3000 diluted).Predicted band size:21kDa.Observed band size:21kDa.
Immunohistochemical of Peroxiredoxin 1/PAG (6A6) in Human tonsil tissue using Peroxiredoxin 1/PAG (6A6) antibody at dilution 1/20
IF analysis of Hela with antibody (Left) and DAPI (Right) diluted at 1:100.
Western blot detection of Peroxiredoxin 1/Prdx1 in Jurkat,CHO-K1,C6,Hela cell lysates using Peroxiredoxin 1/Prdx1 (6A6) Mouse mAb(1:1000 diluted).Predicted band size:21KDa.Observed band size:21KDa.
Western blot analysis of 1) MCF7, 2) Rat Kidney Tissue, 3) Mouse Brain Tissue, diluted at 1:2000.