GST3 (9D4) Mouse mAb
Source: Mouse mAb Catalog No. : AB3490
GST3 (9D4) Mouse mAb (AB3490)
UniProt:P09211
Application:WB,IHC,ICC/IF,FC
Reactivity:Human
Source:Mouse mAbhttp://www.abways.cn/showproduct.asp?cid=AB3490
数据表
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UniProt
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Mol Weight23kDa
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Alternative NamesGSTP1; FAEES3; GST3; Glutathione S-transferase P; GST class-pi; GSTP1-1
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ImmunogenPurified recombinant fragment of human GSTP1 expressed in E. Coli.
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StorageMouse IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeMouse IgG1
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ClonalityMonoclonal
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DescriptionSwiss-Prot Acc.P09211.GSTP1 (glutathione-S-transferase, pi 1), also called GST3/DFN7, is a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. GSTP1 act like a tumor suppressor gene, which when inactivated leads to tumor growth, and the -class glutathione S-transferase is commonly inactivated by somatic CpGisland hypermethylation in cancers of the prostate, liver, and breast. Methylation of regulatory sequences at the GSTP1 gene locus is found in the vast majority (>90%) of prostate carcinomas and is associated with transcriptional down-regulation.
Applications
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ReactivityHuman
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ApplicationWB,IHC,ICC/IF,FC
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Recommended dilutionWB: 1/500-1/1000 IHC: 1/50-1/100 ICC/IF: 1/50-1/200 FC: 1/50-1/100
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Western blot analysis of GST3 (9D4) in PC3 and human cerebellum lysates using GST3 (9D4) antibody. -
Immunohistochemistry analysis of paraffinembedded human prostate tissues using GSTP1 antibody with DAB staining. -
Immunofluorescence analysis of GST3 (9D4) in Confocal HepG2 (left) and L02 (right) cells using GST3 (9D4) antibody(green). Red: Actin filaments have been labeled with DY554 phalloidin. Blue: DRAQ5 fluorescent DNA dye. -
Immunofluorescence analysis of GST3 in PC3 cells using GSTP1 antibody (green). Blue: DRAQ5 fluorescent DNA dye. -
Flow cytometry analysis of K562 stained with GSTP1 antibody (green) and negative control (purple).
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