CD45 (8C1) Mouse mAb
Source: Mouse mAb Catalog No. : AB3505
CD45 (8C1) Mouse mAb (AB3505)
UniProt:P06800
Application:WB,IHC,ICC/IF,FC
Reactivity:Human
Source:Mouse mAbhttp://www.abways.cn/showproduct.asp?cid=AB3505
数据表
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UniProt
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Mol Weight147kDa
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Alternative NamesGP180, L CA, CD45 antigen
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ImmunogenSynthetic Peptide of CD45
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StorageMouse IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeMouse IgG1
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ClonalityMonoclonal
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DescriptionSwiss-Prot Acc.P06800.Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN . Dephosphorylates LYN, and thereby modulates LYN activity.
Applications
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ReactivityHuman
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ApplicationWB,IHC,ICC/IF,FC
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Recommended dilutionWB: 1/500-1/1000 IHC: 1/50-1/100 ICC/IF: 1/50-1/200
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Western blot analysis of CD45 (8C1) in Jurkat lysates using CD45 (8C1) antibody. -
Immunohistochemical analysis of paraffinembedded human tonsils using CD45 (8C1) antibodySodium citrate pH 6.0 was used for antigen retrieval.Negative control was used by secondary antibody only. -
Immunofluorescence analysis of CD45 (8C1) in humanlivercancer tissue using CD45 (8C1) antibody(red),and DAPI (blue).
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