Cytokeratin 17 (8C6) Mouse mAb
Source: Mouse mAb Catalog No. : AB3519
Cytokeratin 17 (8C6) Mouse mAb (AB3519)
UniProt:Q04695
Application:WB,IHC,ICC/IF,IP
Reactivity:Human
Source:Mouse mAbhttp://www.abways.cn/showproduct.asp?cid=AB3519
数据表
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UniProt
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Mol Weight48kDa
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Alternative NamesKeratin; type I cytoskeletal 17; Cytokeratin-17; CK-17; Keratin-17; K17
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ImmunogenSynthetic Peptide of CK17
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StorageMouse IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeMouse IgG1
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ClonalityMonoclonal
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DescriptionSwiss-Prot Acc.Q04695.Type I keratin involved in the formation and maintenance of various skin appendages, specifically in determining shape and orientation of hair . Required for the correct growth of hair follicles, in particular for the persistence of the anagen (growth) state . Modulates the function of TNF-alpha in the specific context of hair cycling. Regulates protein synthesis and epithelial cell growth through binding to the adapter protein SFN and by stimulating Akt/mTOR pathway . Involved in tissue repair. May be a marker of basal cell differentiation in complex epithelia and therefore indicative of a certain type of epithelial
Applications
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ReactivityHuman
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ApplicationWB,IHC,ICC/IF,IP
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Recommended dilutionWB: 1/500-1/1000 IHC: 1/50-1/100 ICC/IF: 1/50-1/200 IP: 1/20
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Western blot analysis of Cytokeratin 17 (8C6) in Hela, MCF7, 293T lysates using Cytokeratin 17 (8C6) antibody. -
Immunohistochemistry analysis of paraffinembedded Humanliver tissue using Cytokeratin 17 (8C6) antibody.Sodium citrate pH 6.0 was used for antigen retrieval.Negative control was used by secondary antibody only. -
Immunofluorescence analysis of Cytokeratin 17 (8C6) in Humanbreast tissue using CK17 antibody(red),and DAPI (blue). -
Immunoprecipitation analysis of Cytokeratin 17 in Hela lysates using Cytokeratin 17 (8C6) antibody.
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