Cytochrome C (7C10) Mouse mAb
Source: Mouse mAb Catalog No. : AB3542
Cytochrome C (7C10) Mouse mAb (AB3542)
UniProt:P99999
Application:WB,IHC,ICC/IF
Reactivity:Human,Mouse,Rat,Chicken
Source:Mouse mAbhttp://www.abways.cn/showproduct.asp?cid=AB3542
数据表
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UniProt
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Mol Weight14kDa
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Alternative NamesCYCS; CYC; Cytochrome c
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ImmunogenRecombinant Protein of CYCS
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StorageMouse IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeMouse IgG1
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ClonalityMonoclonal
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DescriptionSwiss-Prot Acc.P99999.Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.SitesFeature keyPosition(s)Description
Applications
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ReactivityHuman,Mouse,Rat,Chicken
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ApplicationWB,IHC,ICC/IF
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Recommended dilutionWB: 1/500-1/1000 IHC: 1/50-1/100 ICC/IF: 1/50-1/200
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Western blot analysis of Cytochrome c in T47D,3T3,COS7,C6 and Hela lysates using Cytochrome c antibody. -
Immunohistochemistry analysis of paraffinembedded uman tonsil tissue using Cytochrome C (7C10) antibody. -
Immunocytochemistry analysis of Cytochrome C (7C1) (green) in Hela using Cytochrome C (7C1) antibody , and DAPI(blue).
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