Di-Methyl-Histone H3 (Lys79) (8E8) Mouse mAb
Source: Mouse mAb Catalog No. : AB3546
Di-Methyl-Histone H3 (Lys79) (8E8) Mouse mAb (AB3546)
UniProt:P68431
Application:WB
Reactivity:Human,Mouse,Rat
Source:Mouse mAbhttp://www.abways.cn/showproduct.asp?cid=AB3546
数据表
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UniProt
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Mol Weight15kDa
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Alternative NamesH3K79me2; H3 histone; HIST1H3A; Histone cluster 1; H3a
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ImmunogenSynthetic Peptide of Histone H3 (Di Methyl Lys79)
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StorageMouse IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeMouse IgG1
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ClonalityMonoclonal
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DescriptionSwiss-Prot Acc.P68431.Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.MiscellaneousThis histone is only present in mammals and is enriched in acetylation of Lys-15 and dimethylation of Lys-10 (H3K9me2).
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB
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Recommended dilutionWB: 1/500-1/1000
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Western blot analysis of DiMethylHistone H3 (Lys79) in Hela lysates using DiMethylHistone H3 (Lys79) antibody.
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