Histone H3 (10A10) Mouse mAb_单克隆抗体-上海泊湾生物技术有限公司

Histone H3 (10A10) Mouse mAb

Source: Mouse mAb Catalog No. : AB3554

Histone H3 (10A10) Mouse mAb (AB3554)
UniProt:P68431
Application:WB,IP
Reactivity:Human,Mouse,Rat
Source:Mouse mAbhttp://www.abways.cn/showproduct.asp?cid=AB3554

 Datasheet

数据表

UniProt

P68431
Mol Weight

15kDa
Alternative Names

H3 histone; family 3A; H3 histone; family 3B (H3.3B); H3.3A; H3.3B; H33; H3F3; H3F3A; H3F3B; Histone H3.3
Immunogen

Recombinant Protein of Histone H3
Storage

Mouse IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Purification

Affinity-chromatography
Isotype

Mouse IgG1
Clonality

Monoclonal
Description

Swiss-Prot Acc.P68431.Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.MiscellaneousThis histone is only present in mammals and is enriched in acetylation of Lys-15 and dimethylation of Lys-10 (H3K9me2).

Applications

Reactivity

Human,Mouse,Rat
Application

WB,IP
Recommended dilution

WB: 1/500-1/1000 IP: 1/20

Western blot analysis of Histone H3 (10A10) in C6,3T3,Hela lysates using Histone H3 (10A10) antibody.
Western blot analysis of Histone H3 in Hela, Raw 264.7, Rat Testis lysates using Histone H3 (10A10) antibody.
Immunoprecipitation analysis of Histone H3 (10A10) in Hela lysates using Histone H3 (1A1) antibody.