IKB beta (5H3) Mouse mAb
Source: Mouse mAb Catalog No. : AB3567
IKB beta (5H3) Mouse mAb (AB3567)
UniProt:Q15653
Application:IHC
Reactivity:Human,Mouse,Rat
Source:Mouse mAbhttp://www.abways.cn/showproduct.asp?cid=AB3567
数据表
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UniProt
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Mol Weight48kDa
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Alternative NamesNFKBIB; IKBB; TRIP9; NF-kappa-B inhibitor beta; NF-kappa-BIB; I-kappa-B-beta; IkB-B; IkB-beta; IkappaBbeta; Thyroid receptor-interacting protein 9; TR-interacting protein 9; TRIP-9
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ImmunogenPurified recombinant protein expressed in E.coli.
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StorageMouse IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeMouse IgG1
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ClonalityMonoclonal
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DescriptionSwiss-Prot Acc.Q15653.Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationIHC
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Recommended dilutionIHC: 1/50-1/100
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Immunohistochemistry analysis of paraffinembedded Human Lung Carcinoma using IKB beta (5H3) antibody. -
Immunohistochemical analysis of paraffinembedded human tonsils using IKB beta (5H3) antibody.
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