MLKL (5E3) Mouse mAb
Source: Mouse mAb Catalog No. : AB3604
MLKL (5E3) Mouse mAb (AB3604)
UniProt:Q8NB16
Application:IHC
Reactivity:Human
Source:Mouse mAbhttp://www.abways.cn/showproduct.asp?cid=AB3604
数据表
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UniProt
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Mol Weight54kDa
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Alternative NamesMixed lineage kinase domain like protein, FLJ34389
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ImmunogenSynthetic peptide conjugated to KLH.
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StorageMouse IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeMouse IgG1
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ClonalityMonoclonal
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DescriptionSwiss-Prot Acc.Q8NB16.Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.
Applications
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ReactivityHuman
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ApplicationIHC
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Recommended dilutionIHC: 1/50-1/100