Phospho-TAK1 (Thr184) Antibody
Source: Rabbit pAb Catalog No. : AY0141
Phospho-TAK1 (Thr184) Antibody (AY0141)
UniProt:O43318
Application:WB
Reactivity:Human:T184,Mouse:T184,Rat:T184
Source:Rabbit pAbhttp://www.abways.cn/showproduct.asp?cid=AY0141
数据表
-
UniProt
-
Mol Weight75kDa
-
Alternative NamesEC 2.7.11.25, M3K7, MAP3K7, Mitogen-activated protein kinase kinase kinase 7, TGF-beta- activated kinase 1, Transforming growth factor-beta-activated kinase 1, kinase TAK1
-
ImmunogenThe antiserum was produced against synthesized phosphopeptide derived from human TAK1 around the phosphorylation site of threonine 184 (I-Q-TP-H-M).
-
StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
-
PurificationAffinity-chromatography
-
IsotypeRabbit IgG
-
ClonalityPolyclonal
-
DescriptionSerine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Mediates signal transduction of TRAF6, various cytokines including interleukin-1 (IL-1), transforming growth factor-beta (TGFB), TGFB-related factors like BMP2 and BMP4, toll-like receptors (TLR), tumor necrosis factor receptor CD40 and B-cell receptor (BCR). Ceramides are also able to activate MAP3K7/TAK1.
Applications
-
ReactivityHuman:T184,Mouse:T184,Rat:T184
-
ApplicationWB
-
Recommended dilutionWB: 1:500~1:3000 ELISA: 1:1000
-
Western blot analysis of extracts from HepG2 cells, treated with TNF (20ng/ml, 5mins), using TAK1 (Phospho-Thr184) antibody. -
Western blot analysis of extracts from 293 cells (Lane 2), using TAK1 (Phospho-Thr184) antibody. The lane on the left is treated with synthesized peptide.
销售咨询
一键电话