Phospho-LAT (Tyr191) Antibody
Source: Rabbit pAb Catalog No. : AY0148
Phospho-LAT (Tyr191) Antibody (AY0148)
UniProt:O43561
Application:WB,IHC,ELISA
Reactivity:Human:Y191,Mouse:Y195,Rat:Y195
Source:Rabbit pAbhttp://www.abways.cn/showproduct.asp?cid=AY0148
数据表
-
UniProt
-
Mol Weight28 kDa
-
Alternative Names36 kDa phospho-tyrosine adaptor protein, Linker for activation of T cells, p36-38, pp36
-
ImmunogenThe antiserum was produced against synthesized phosphopeptide derived from human LAT around the phosphorylation site of tyrosine 191 (R-E-YP-V-N).
-
StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
-
PurificationAffinity-chromatography
-
IsotypeRabbit IgG
-
ClonalityPolyclonal
-
DescriptionInvolved in FCGR3 (low affinity immunoglobulin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Couples activation of these receptors and their associated kinases with distal intracellular events such as mobilization of intracellular calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1, GRB2, GRAP2, and other signaling molecules
Applications
-
ReactivityHuman:Y191,Mouse:Y195,Rat:Y195
-
ApplicationWB,IHC,ELISA
-
Recommended dilutionWB: 1:500~1:3000 IHC: 1:50~1:100 ELISA: 1:1000
-
Western blot analysis of extracts from NIH/3T3 cells, using LAT (Phospho-Tyr191) antibody. -
Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue using LAT (Phospho-Tyr191) antibody.
销售咨询
一键电话