Phospho-CREB (Thr100) Antibody
Source: Rabbit pAb Catalog No. : AY0332
Phospho-CREB (Thr100) Antibody (AY0332)
UniProt:P16220
Application:WB
Reactivity:Human:T100,Mouse:T100,Rat:T100
Source:Rabbit pAbhttp://www.abways.cn/showproduct.asp?cid=AY0332
数据表
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UniProt
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Mol Weight40 kDa
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Alternative NamescAMP responsive element binding protein 1; cAMP-response element binding protein; CREB-1; CREB1
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ImmunogenThe antiserum was produced against synthesized phosphopeptide derived from human CREB around the phosphorylation site of threonine 100 (S-G-TP-Q-I).
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityPolyclonal
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DescriptionPhosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-119 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells.
Applications
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ReactivityHuman:T100,Mouse:T100,Rat:T100
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ApplicationWB
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Recommended dilutionWB: 1:500~1:3000 ELISA: 1:20000
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Western blot analysis of extracts from HUVEC cells, treated with etoposide (25uM, 24hours), using CREB (Phospho-Thr100) antibody.
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