Phospho-PLCG2 (Tyr1217) Antibody
Source: Rabbit pAb Catalog No. : AY0335
Phospho-PLCG2 (Tyr1217) Antibody (AY0335)
UniProt:P16885
Application:WB,IHC,IF
Reactivity:Human:Y1217,Mouse:Y1217,Rat:Y1217
Source:Rabbit pAbhttp://www.abways.cn/showproduct.asp?cid=AY0335
数据表
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UniProt
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Mol Weight148 kDa
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Alternative Names1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2, EC 3.1.4.11, PLC-IV, PLC-gamma2, Phospholipase C-gamma-2
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ImmunogenThe antiserum was produced against synthesized phosphopeptide derived from human PLCG2 around the phosphorylation site of tyrosine 1217 (L-F-L-YP-D-T).
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityPolyclonal
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DescriptionThe production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. It is a crucial enzyme in transmembrane signaling.
Applications
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ReactivityHuman:Y1217,Mouse:Y1217,Rat:Y1217
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ApplicationWB,IHC,IF
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Recommended dilutionWB: 1:500~1:3000 IHC: 1:50~1:100 IF: 1:100~1:500 ELISA: 1:1000
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Western blot analysis of extracts from Jurkat cells, treated with UV (15mins), using PLCG2 (Phospho-Tyr1217) antibody. -
Immunohistochemistry analysis of paraffin-embedded human tonsil tissue using PLCG2 (Phospho-Tyr1217) antibody.
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