P25963

I-kappa-B-alpha, IKBA, IkappaBalpha, MAD3, Major histocompatibility complex enhancer-binding protein MAD3, NF-kappaB inhibitor alpha, NFKBI, NFKBIA, RL/IF-1

The antiserum was produced against synthesized phosphopeptide derived from human IκB-α around the phosphorylation site of tyrosine 42 (E-E-YP-E-Q).

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

Affinity-chromatography

Rabbit IgG

Polyclonal

Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.

Human:Y42,Mouse:Y42,Rat:Y42

IHC

IHC: 1:50~1:100 ELISA: 1:10000