Phospho-IRS-1 (Ser1101) Antibody
Source: Rabbit pAb Catalog No. : AY0439
Phospho-IRS-1 (Ser1101) Antibody (AY0439)
UniProt:P35568
Application:WB,IHC
Reactivity:Human:S1101,Mouse:S1097,Rat:S1100
Source:Rabbit pAbhttp://www.abways.cn/showproduct.asp?cid=AY0439
数据表
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UniProt
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Mol Weight132 kDa
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Alternative NamesIRS-1, IRS1, Insulin receptor substrate-1
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ImmunogenThe antiserum was produced against synthesized phosphopeptide derived from human IRS-1 around the phosphorylation site of serine 1101 (H-S-SP-E-T).
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityPolyclonal
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DescriptionIRS-1 is an adaptor protein that is one of the major substrates of the insulin receptor kinase. Contains multiple tyrosine phosphorylation motifs that serve as docking sites for SH2-domain-containing proteins including phosphatidylinositol 3-kinase p85 subunit and GRB-2.
Applications
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ReactivityHuman:S1101,Mouse:S1097,Rat:S1100
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ApplicationWB,IHC
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Recommended dilutionWB: 1:500~1:3000 IHC: 1:50~1:100 ELISA: 1:5000
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Western blot analysis of extracts from COS7 cells, treated with Calyculin A (50ng/ml, 30mins), using IRS-1 (Phospho-Ser1101) Antibody. -
Immunohistochemical analysis of paraffin-embedded human colon carcinoma tissue using IRS-1 (Phospho-Ser1101) Antibody.
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