Phospho-VEGFR2 (Tyr1175) Antibody
Source: Rabbit pAb Catalog No. : AY0441
Phospho-VEGFR2 (Tyr1175) Antibody (AY0441)
UniProt:P35968
Application:WB,IHC
Reactivity:Human:Y1175,Mouse:Y1173,Rat:Y1171
Source:Rabbit pAbhttp://www.abways.cn/showproduct.asp?cid=AY0441
数据表
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UniProt
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Mol Weight152kDa
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Alternative NamesEC 2.7.10.1; FLK1; KDR; kinase insert domain receptor; protein-tyrosine kinase receptor Flk-1; vascular endothelial growth factor receptor 2; VGFR2; VGR2
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ImmunogenThe antiserum was produced against synthesized phosphopeptide derived from human VEGFR2 around the phosphorylation site of tyrosine 1175 (K-D-YP-I-V).
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityPolyclonal
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DescriptionVEGFR-2 is a receptor tyrosine kinase of the VEGFR family. High affinity receptor for VEGF and VEGF-C. Ligand binding induces autophosphorylation and activation. Activated receptor recruits proteins including Shc, GRB2, PI3K, Nck, SHP-1 and SHP-2.
Applications
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ReactivityHuman:Y1175,Mouse:Y1173,Rat:Y1171
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ApplicationWB,IHC
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Recommended dilutionWB: 1:500~1:3000 IHC: 1:50~1:100 ELISA: 1:10000
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Western blot analysis of extracts from NIH-3T3 cells and HUVEC cells treated with EGF (200ng/ml, 30mins), using VEGFR2 (Phospho-Tyr1175) antibody.
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