P41182

90kDa

B-cell CLL/lymphoma 6; B-cell lymphoma 6 protein; B-cell lymphoma 6 protein homolog; Bcl-5; Bcl5; Bcl6; LAZ-3 protein; LAZ3; Zinc finger protein 51; ZNF51

The antiserum was produced against synthesized non-phosphopeptide derived from human Bcl-6 around the phosphorylation site of serine 333 (P-Q-SP-P-Q).

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

Affinity-chromatography

Rabbit IgG

Polyclonal

Transcriptional repressor mainly required for germinal center (GC) formation and antibody affinity maturation which has different mechanisms of action specific to the lineage and biological functions. Forms complexes with different corepressors and histone deacetylases to repress the transcriptional expression of different subsets of target genes. Represses its target genes by binding directly to the DNA sequence 5'-TTCCTAGAA-3' (BCL6-binding site) or indirectly by repressing the transcriptional activity of transcription factors.

Human,Mouse,Rat

WB

WB: 1:500~1:3000 ELISA: 1:40000