Histone H3 Antibody
Source: Rabbit pAb Catalog No. : AY0585
Histone H3 Antibody (AY0585)
UniProt:P68431
Application:WB,IHC
Reactivity:Human,Mouse,Rat
Source:Rabbit pAb
References（1）
http://www.abways.cn/showproduct.asp?cid=AY0585
数据表
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UniProt
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Mol Weight15 kDa
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Alternative NamesH3/a; H3/c; H3/d; H3/f; H3/h; H3/i; H3/j; H3/k; H3/l; H31; HIST1H3A; histone H3.1
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ImmunogenThe antiserum was produced against synthesized non-phosphopeptide derived from human Histone H3 around the phosphorylation site of threonine 3 (A-R-TP-K-Q).
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityPolyclonal
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DescriptionCore component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB,IHC
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Recommended dilutionWB: 1:500~1:3000 IHC: 1:50~1:100 ELISA: 1:5000
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Western blot analysis of extracts from A549 cells, using Histone H3 antibody. -
Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using Histone H3 antibody.
引用文献（1条）
Type 2 diabetes-induced overactivation of P300 contributes to skeletal muscle atrophy by inhibiting autophagic flux-LIFE SCIENCES (LIFE SCI)
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