Trk B Antibody
Source: Rabbit pAb Catalog No. : AY0754
Trk B Antibody (AY0754)
UniProt:Q16620
Application:WB,IHC,ELISA
Reactivity:Human,Mouse,Rat
Source:Rabbit pAbhttp://www.abways.cn/showproduct.asp?cid=AY0754
数据表
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UniProt
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Mol Weight92kDa
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Alternative NamesBDNF/NT-3 growth factors receptor precursor, EC 2.7.10.1, GP145-TrkB, GP145-TrkB/GP95-TrkB, NTRK2, Trk-B, TrkB tyrosine kinase, kinase TrkB
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ImmunogenThe antiserum was produced against synthesized non-phosphopeptide derived from human Trk B around the phosphorylation site of tyrosine 515 (P-Q-YP-F-G).
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityPolyclonal
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DescriptionThe family of Trk receptor tyrosine kinases consists of TrkA, TrkB, and TrkC. While the sequence of these family members is highly conserved, they are activated by different neurotrophins: TrkA by NGF, TrkB by BDNF or NT4, and TrkC by NT3. Plays a role in learning and memory by regulating both short term synaptic function and long-term potentiation. PLCG1 also leads to NF-Kappa-B activation and the transcription of genes involved in cell survival.
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB,IHC,ELISA
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Recommended dilutionWB: 1:500~3000 IHC: 1:50~100 ELISA: 1:10000
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Western blot analysis of extracts from 3T3 cells treated with PBS (60min), using Trk B antibody. -
Immunohistochemical analysis of paraffin-embedded human brain tissue using Trk B antibody.
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