ARHGEF2 Antibody
Source: Rabbit pAb Catalog No. : AY1253
ARHGEF2 Antibody (AY1253)
UniProt:Q92974
Application:WB
Reactivity:Human
Source:Rabbit pAbhttp://www.abways.cn/showproduct.asp?cid=AY1253
数据表
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UniProt
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Mol Weight101 KD
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Alternative NamesGEF-H1; GEFH1; Guanine nucleotide exchange factor GEF-H1; proliferating cell nucleolar antigen p40; rho/rac guanine nucleotide exchange factor 2
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ImmunogenA synthesized peptide derived from human ARHGEF2
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityPolyclonal
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DescriptionActivates Rho-GTPases by promoting the exchange of GDP for GTP. May be involved in epithelial barrier permeability, cell motility and polarization, dendritic spine morphology, antigen presentation, leukemic cell differentiation, cell cycle regulation, innate immune response, and cancer. Binds Rac-GTPases, but does not seem to promote nucleotide exchange activity toward Rac-GTPases, which was uniquely reported in PubMed:9857026.
Applications
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ReactivityHuman
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ApplicationWB
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Recommended dilutionWB 1:500~1:1000
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Western blot analysis of extracts from RAW264.7 cells, using ARHGEF2 antibody.
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