DNMT3B Antibody
Source: Rabbit pAb Catalog No. : AY1982
DNMT3B Antibody (AY1982)
UniProt:Q9UBC3
Application:WB,IHC,ICC/IF
Reactivity:Human
Source:Rabbit pAbhttp://www.abways.cn/showproduct.asp?cid=AY1982
数据表
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UniProt
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Mol Weight96 KD
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Alternative NamesDNA (cytosine-5)-methyltransferase 3B, EC 2.1.1.37, Dnmt3b, DNA methyltransferase HsaIIIB, DNA MTase HsaIIIB, M.HsaIIIB, DNMT3B
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ImmunogenA synthesized peptide derived from human DNMT3B
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityPolyclonal
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DescriptionRequired for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. May preferentially methylates nucleosomal DNA within the nucleosome core region. May function as transcriptional co-repressor by associating with CBX4 and independently of DNA methylation. Seems to be involved in gene silencing (By similarity).
Applications
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ReactivityHuman
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ApplicationWB,IHC,ICC/IF
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Recommended dilutionWB 1:500~1:1000 IHC: 1:50~1:200 IF/ICC 1:100-1:500
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Western blot analysis of extracts from HT-29 cells, using DNMT3B antibody. -
Immunohistochemistry analysis of paraffin-embedded human liver carcinoma tissue using DNMT3B antibody. -
Immunofluorescence analysis of HeLa cells, using DNMT3B antibody.
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