LFNG Antibody
Source: Rabbit pAb Catalog No. : AY2846
LFNG Antibody (AY2846)
UniProt:Q8NES3
Application:WB
Reactivity:Human,Mouse,Rat
Source:Rabbit pAbhttp://www.abways.cn/showproduct.asp?cid=AY2846
数据表
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UniProt
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Mol Weight42 KD
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Alternative Namesbeta-1,3-N-acetylglucosaminyltransferase lunatic fringe; EC 2.4.1.222; LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase; O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase; SCDO3
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ImmunogenA synthesized peptide derived from human LFNG
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityPolyclonal
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DescriptionGlycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Modulates NOTCH1 activity by modifying O-fucose residues at specific EGF-like domains resulting in inhibition of NOTCH1 activation by JAG1 and enhancement of NOTCH1 activation by DLL1 via an increase in its binding to DLL1 (By similarity).
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB
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Recommended dilutionWB 1:500~1:1000
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Western blot analysis of extracts from MCF-7 cells and HUVEC cells, using LFNG antibody.
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