Bak Antibody
Source: Rabbit pAb Catalog No. : CY1005
Bak Antibody (CY1005)
UniProt:Q16611
Application:WB,IHC
Reactivity:Human,Mouse
Source:Rabbit pAbhttp://www.abways.cn/showproduct.asp?cid=CY1005
数据表
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UniProt
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Mol Weight25kDa
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Alternative NamesApoptosis regulator BAK; BAK; BAK-LIKE; BAK1; Bcl-2 homologous antagonist/killer; Bcl-2-like protein 7; BCL2-antagonist/killer 1; Bcl2-L-7; BCL2-like 7 protein; BCL2L7; CDN1; MGC117255; MGC3887; pro-apoptotic protein BAK
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ImmunogenA synthesized peptide derived from human Bak
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityPolyclonal
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DescriptionBak1 In the presence of an appropriate stimulus, accelerates programmed cell death by binding to, and antagonizing the anti- apoptotic action of BCL2 or its adenovirus homolog E1B 19k protein. Low micromolar levels of zinc ions inhibit the promotion of apoptosis. Belongs to the Bcl-2 family. Interacts with BCL2A1. Homodimer. Formation of the homodimer is zinc-dependent. Forms heterodimers with BCL2, E1B 19k protein, and BCL2L1 isoform Bcl-X(L). Interacts with myxoma virus protein M11L
Applications
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ReactivityHuman,Mouse
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ApplicationWB,IHC
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Recommended dilutionWB 1:500~1:3000 IHC 1:50~1:200
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Western blot analysis of extracts from 293 cells, using Bak antibody. -
Immunohistochemical analysis of paraffin-embedded human skeletal muscle tissue, using Bak antibody.
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