Claudin 1 Antibody
Source: Rabbit pAb Catalog No. : CY1013
Claudin 1 Antibody (CY1013)
UniProt:O95832
Application:WB,IHC
Reactivity:Human,Mouse,Rat
Source:Rabbit pAbhttp://www.abways.cn/showproduct.asp?cid=CY1013
数据表
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UniProt
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Mol Weight22kDa
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Alternative Namesclaudin 1; Claudin-1; CLD1; CLDN1; ILVASC; SEMP1; Senescence-associated epithelial membrane protein; senescence-associated epithelial membrane protein 1
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ImmunogenA synthesized peptide derived from human Claudin 1
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityPolyclonal
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Descriptionclaudin 1 Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity. Acts as a co- receptor for HCV entry into hepatic cells. Belongs to the claudin family. Can form homo- and heteropolymers with other CLDN. Homopolymers interact with CLDN3, but not CLDN2, homopolymers. Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3. Interacts with MPDZ and INADL. May interact with HCV E1 and E2 proteins.
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB,IHC
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Recommended dilutionWB 1:500~1:3000 IHC 1:50~1:200
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Western blot analysis of extracts from HeLa cells, using Claudin 1 antibody.
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