E2F6 Antibody
Source: Rabbit pAb Catalog No. : CY1063
E2F6 Antibody (CY1063)
UniProt:O75461
Application:WB,IHC
Reactivity:Human,Mouse,Rat
Source:Rabbit pAb
References（1）
http://www.abways.cn/showproduct.asp?cid=CY1063
数据表
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UniProt
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Mol Weight31kDa
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Alternative NamesE2F transcription factor 6; E2F transcription factor 6, isoform 1; E2F-6; E2F6; MGC111545; Transcription factor E2F6
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ImmunogenA synthesized peptide derived from human E2F6
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityPolyclonal
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DescriptionE2F6 Inhibitor of E2F-dependent transcription. Binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3'. Has a preference for the 5'-TTTCCCGC-3' E2F recognition site. E2F-6 lacks the transcriptional activation and pocket protein binding domains. Appears to regulate a subset of E2F-dependent genes whose products are required for entry into the cell cycle but not for normal cell cycle progression. May silence expression via the recruitment of a chromatin remodeling complex containing histone H3-K9 methyltransferase activity.
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB,IHC
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Recommended dilutionWB 1:500~1:3000 IHC 1:50~1:200
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Western blot analysis on HepG2 cell lysate using E2F6 Antibody
引用文献（1条）
Hepatic nuclear factor 4 alpha promotes the ferroptosis of lung adenocarcinoma via transcriptional activation of cytochrome P450 oxidoreductase-PeerJ
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