Q9UNS2

47kDa

COP9 complex subunit 3; COP9 constitutive photomorphogenic homolog subunit 3 (Arabidopsis); COP9 signalosome complex subunit 3; COPS3; CSN3; JAB1-containing signalosome subunit 3; SGN3; Signalosome subunit 3

A synthesized peptide derived from human COPS3

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

Affinity-chromatography

Rabbit IgG

Polyclonal

COPS3 Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases.

Human,Mouse,Rat

WB,ICC/IF

WB 1:500~1:3000 IF/ICC 1:100~1:500