NKX3.1 Antibody
Source: Rabbit pAb Catalog No. : CY1227
NKX3.1 Antibody (CY1227)
UniProt:Q99801
Application:IHC
Reactivity:Human
Source:Rabbit pAbhttp://www.abways.cn/showproduct.asp?cid=CY1227
数据表
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UniProt
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Mol Weight38kDa
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Alternative NamesBAPX2; Homeobox protein NK-3 homolog A; Homeobox protein Nkx-3.1; NK homeobox, family 3, A; NK3 homeobox 1; NK3 transcription factor homolog A; NK3 transcription factor related, locus 1; NKX3; NKX3-1; NKX3.1; NKX31; NKX3A
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ImmunogenA synthesized peptide derived from human NKX3.1
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityPolyclonal
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DescriptionNKX3-1 Transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. Play an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Act as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells. Interacts with serum response factor (SRF).
Applications
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ReactivityHuman
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ApplicationIHC
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Recommended dilutionIHC 1:50-1:200



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