P78324

55kDa

Tyrosine-protein phosphatase non-receptor type substrate 1; SIRPA; SHP substrate 1; SHPS-1; CD172a; BIT, MFR, MYD1, PTPNS1, SHPS1, SIRP; CD172 antigen-like family member A; Inhibitory receptor SHPS-1; SIRP alpha 1;

A synthesized peptide derived from human SHPS1

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

Affinity-chromatography

Rabbit IgG

Polyclonal

SHPS1 Immunoglobulin-like cell surface receptor for CD47. Acts as docking protein and induces translocation of PTPN6, PTPN11 and other binding partners from the cytosol to the plasma membrane. Supports adhesion of cerebellar neurons, neurite outgrowth and glial cell attachment. May play a key role in intracellular signaling during synaptogenesis and in synaptic function. Involved in the negative regulation of receptor tyrosine kinase-coupled cellular responses induced by cell adhesion, growth factors or insulin. Mediates negative regulation of phagocytosis, mast cell activation and dendritic cell activation.

Human,Mouse,Rat

WB,IHC

WB 1:500~1:3000 IHC 1:50~1:200