GSK3 beta Antibody
Source: Rabbit mAb Catalog No. : CY2434
GSK3 beta Antibody (CY2434)
UniProt:P49841
Application:WB,IHC,ICC/IF,FC
Reactivity:Human,Mouse
Source:Rabbit mAb
References（1）
http://www.abways.cn/showproduct.asp?cid=CY2434
数据表
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UniProt
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Mol Weight46kDa
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Alternative Namesglycogen synthase kinase 3 beta; Glycogen synthase kinase-3 beta; GSK-3 beta; GSK3B; GSK3beta isoform;
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ImmunogenA synthesized peptide derived from human GSK3 beta
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionGlycogen synthase kinase-3 (GSK3) is a proline-directed serine-threonine kinase that was initially identified as a phosphorylating and inactivating glycogen synthase .GSK3B is involved in energy metabolism, neuronal cell development, and body pattern formation.In skeletal muscle, it contributes to insulin regulation of glycogen synthesis by phosphorylating and inhibiting GYS1 activity and hence glycogen synthesis.
Applications
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ReactivityHuman,Mouse
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ApplicationWB,IHC,ICC/IF,FC
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Recommended dilutionWB 1:500~1:3000 IHC 1:50~1:200 ICC/IF 1:100~1:500 FC 1:200~1:500
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All lanes use the Antibody at 1:4K dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature. -
Immunohistochemical analysis of paraffin-embedded Human colon cancer, using the Antibody at 1:100 dilution. -
Immunohistochemical analysis of paraffin-embedded Human prostate cancer, using the Antibody at 1:100 dilution. -
Immunohistochemical analysis of paraffin-embedded Human small cell lung cancer , using the Antibody at 1:100 dilution. -
Immunohistochemical analysis of paraffin-embedded Human pancreatic cancer, using the Antibody at 1:400 dilution. -
Immunofluorescent analysis using the Antibody at 1:50 dilution. -
Western blot analysis of GSK3 beta expression in HEK293 cell lysate. -
Immunohistochemical analysis of paraffin-embedded human colon carcinome, using GSK3 beta Antibody. -
Immunofluorescent analysis of Hela cells, using GSK3 beta Antibody . -
All lanes use the Antibody at 1:1500 dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:5K dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:5K dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:5K dilution for 1 hour at room temperature.
引用文献（1条）
Budding uninhibited by benzimidazoles 1 promotes cell proliferation, invasion, and epithelial-mesenchymal transition via the Wnt/β-catenin signaling in glioblastoma-Heliyon
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