Cyclin D2 Antibody
Source: Rabbit pAb Catalog No. : CY2970
Cyclin D2 Antibody (CY2970)
UniProt:P30279
Application:WB
Reactivity:Human,Mouse,Rat
Source:Rabbit pAbhttp://www.abways.cn/showproduct.asp?cid=CY2970
数据表
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UniProt
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Mol Weight33 kDa
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Alternative Namescyclin D2; G1/S-specific cyclin D2
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ImmunogenA synthesized peptide derived from human Cyclin D2
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityPolyclonal
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DescriptionRegulatory component of the cyclin D2-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase.
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB
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Recommended dilutionWB 1:500-1:2000
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Western blot analysis of Cyclin D2 expression in 293 cells
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