beta Catenin Antibody
Source: Rabbit mAb Catalog No. : CY3523
beta Catenin Antibody (CY3523)
UniProt:P35222
Application:WB,IHC,ICC/IF,IP
Reactivity:Human,Mouse,Rat
Source:Rabbit mAb
References（6）
http://www.abways.cn/showproduct.asp?cid=CY3523
数据表
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UniProt
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Mol Weight92kDa
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Alternative NamesCATNB; CTNB1; CTNNB; catenin beta;
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ImmunogenA synthesized peptide derived from human beta Catenin
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionBeta-catenin is an adherens junction protein. Adherens junctions (AJs; also called the zonula adherens) are critical for the establishment and maintenance of epithelial layers, such as those lining organ surfaces. AJs mediate adhesion between cells, communicate a signal that neighboring cells are present, and anchor the actin cytoskeleton. In serving these roles, AJs regulate normal cell growth and behavior.
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB,IHC,ICC/IF,IP
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Recommended dilutionWB 1:1000~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50
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All lanes use the Antibody at 1:1W dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:1W dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:1W dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:1W dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:1W dilution for 1 hour at room temperature. -
Immunohistochemical analysis of paraffin-embedded Human testis cancer, using the Antibody at 1:1000 dilution. -
Immunohistochemical analysis of paraffin-embedded Human small cell lung cancer , using the Antibody at 1:1000 dilution. -
Immunohistochemical analysis of paraffin-embedded Human astrocytoma, using the Antibody at 1:1000 dilution. -
Western blot analysis of beta catenin expression in (1) A431 cell lysates; (2)PC-12 cell lysates. -
Immunofluorescent analysis of A431 cells, using beta Catenin Antibody . -
Histone methyltransferase SETD2 regulates osteosarcoma cell growth and chemosensitivity by suppressing Wnt/β-catenin signaling. -Biochemical and Biophysical Research Communications
引用文献（6条）
Histone methyltransferase SETD2 regulates osteosarcoma cell growth and chemosensitivity by suppressing Wnt/β-catenin signaling.-Biochemical and Biophysical Research Communications
REC8 enhances stemness and promotes metastasis of colorectal cancer through BTK/Akt/β-catenin signaling pathway-Translational Oncology (TRANSL ONCOL）
SET Domain Containing 2 Deficiency in Myelodysplastic Syndrome-Frontiers in Genetics (FRONT GENET)
ONECUT2 which is targeted by hsa-miR-15a-5p enhances stemness maintenance of gastric cancer stem cells-Experimental Biology and Medicine (EXP BIOL MED)
ARHGAP9 knockdown promotes lung adenocarcinoma metastasis by activating Wnt/β-catenin signaling pathway via suppressing DKK2-GENOMICS
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